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CyFlow™ CD4 PerCP
Application: | Flow cytometry |
Format/Fluorochrome: | PerCP |
Clone: | GK1.5 |
Alternative Name: | Leu3a, T4 |
Antigen: | CD4 |
Emission Maximum: | 678 nm |
Excitation Maximum: | 482 to 490 nm |
Field of Interest: | Immunophenotyping, MHC |
Clonality: | monoclonal |
Target Species: | Mouse |
Laser: | Blue, Green |
Isotype: | IgG2b |
Regulatory Status: | RUO |
Source Species: | Rat |
Order number: | AJ556990 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
CD4 is a single chain transmembrane glycoprotein of immunoglobulin supergene family. In its... more
Product information "CyFlow™ CD4 PerCP"
CD4 is a single chain transmembrane glycoprotein of immunoglobulin supergene family. In its extracellular region there are 4 immunoglobulin-like domains (1 Ig-like V-type and 3 Ig-like C2-type). The intracellular region of CD4 associates with p56Lck, a Src-like protein tyrosine kinase. It was described that CD4 segregates into specific detergent-resistant T-cell membrane microdomains. CD4 binds to MHC class II molecules (by CDR2-like region in CD4 domain 1), HIV envelope protein gp120 (by CDR2-like region in CD4 domain 1) and other ligands, such as IL-16 (by to CD4 domain 3) or L-selectin. CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection. CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction. Defects in antigen presentation (MHC class II) cause dysfunction of CD4+ T-cells and their almost complete absence in patients blood, tissue and organs (SCID immunodeficiency).
Technical Data Sheet
- CyFlow™ CD4 PerCP-Cy5.5 (MEM-241) CK833676 TDS US,CA EN.pdf
- CyFlow CD4 PerCP (MEM-241) AS415231 TDS RUO.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) AZ142430 TDS RUO.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK833676 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU DE DE.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU CZ CZ.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU DK DK.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU ES ES.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU FR FR.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU GB EN.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU GR EL.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU IT IT.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU NL NL.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU NO NO.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU PL PL.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU PT PT.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU RU RU.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU SE SV.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU SK SK.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) BA577933 IFU TR TR.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU CZ CZ.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU DE DE.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU DK DK.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU ES ES.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU FR FR.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU GB EN.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU GR EL.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU IT IT.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU NL NL.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU NO NO.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU PL PL.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU PT PT.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU RU RU.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU SE SV.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU SK SK.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU TR TR.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU BG BG.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU HR HR.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU RO RO.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU SI SL.pdf
- CyFlow CD4 PerCP-Cy5.5 (MEM-241) CK649514 IFU RS SR.pdf
ECDoC
Certificate Of Analysis
- CyFlow CD4 PerCP-Cy5.5 BA577933 COA 901986.pdf
- CyFlow CD4 PerCP-Cy5.5 CK833676 COA 901986.pdf
- CyFlow CD4 PerCP-Cy5.5 BA577933 COA 903338.pdf
- CyFlow CD4 PerCP-Cy5.5 CK833676 COA 903338.pdf
- CyFlow CD4 PerCP-Cy5.5 CK833676 COA 903821.pdf
- CyFlow CD4 PerCP-Cy5.5 CK649514 COA 905008.pdf
- CyFlow CD4 PerCP-Cy5.5 CK833676 COA 905008.pdf
- CyFlow CD4 PerCP-Cy5.5 BA577933 COA 905008.pdf
- CyFlow CD4 PerCP-Cy5.5 CK833676 COA 905966.pdf
- CyFlow CD4 PerCP-Cy5.5 BA577933 COA 905966.pdf
- CyFlow CD4 PerCP-Cy5.5 CK649514 COA 905966.pdf
- CyFlow CD4 PerCP-Cy5.5 CK833676 COA 906603.pdf
- CyFlow CD4 PerCP-Cy5.5 BA577933 COA 906603.pdf
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